Hypercalcemia, multiple osteolytic lesions, and acute renal failure: a rare presentation of B-cell acute lymphoblastic leukemia

نویسندگان

  • Vandana Puri
  • Pooja Sharma
  • Sundaram Gopalakrishnan
  • Meera Sikka
  • Rajnish Avasthi
چکیده

Urea 171 mg/dL 15–40 mg/dL Creatinine 3.6 mg/dL 0.9–1.8 mg/dL Sodium 141 mEq/L 133–145 mEq/L Potassium 4.3 mEq/L 3.8–5.0 mEq/L Chloride 107 mEq/L 96–106 mEq/L Calcium 13 mg/dL 8.5–11 mg/dL Phosphate 2.3 mg/dL 2.4–4.1 mg/dL Uric acid 7.6 mg/dL 1.9–7.5 mg/dL Total bilirubin 0.4 mg/dL 0–2 mg/dL Direct bilirubin 0.2 mg/dL 0.2–1.0 mg/dL AST 6 U/L 10–40 U/L ALT 26 U/L 7–56 U/L Total protein 6.8 gm/dL 0.3–8.0 gm/dL Albumin 2.7 gm/dL 3.5–5.5 gm/dL A/G ratio 0.65 0.8–2.0

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REFERENCES 1. Young JL Jr, Miller RW. Incidence of malignant tumors in U. S. children. J Pediatr 1975;86:254-8. 2. Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med 2004;350:1535-48. 3. Jonsson OG, Sartain P, Ducore JM, Buchanan GR. Bone pain as an initial symptom of childhood acute lymphoblastic leukemia: association with nearly normal hematologic indexes. J Pediatr 19...

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Osteolytic bone lesions, severe hypercalcemia without circulating blasts: unusual presentation of childhood acute lymphoblastic leukemia

Hypercalcemia and severe osteolytic lesions are rare complications of acute lymphoblastic leukemia (ALL) in childhood. We report a case of a 3 years old boy who presented with prolonged fever, nausea, vomiting and increasing lower limbs pain. Skeletal X-rays and CT scan showed severe osteolytic lesions of the skull and extremities. Her physical examination showed multiple cervical lymph nodes. ...

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Multiple Osteolytic Lesions Causing Hypercalcemia: A Rare Presentation of Acute Lymphoblastic Leukemia

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عنوان ژورنال:

دوره 52  شماره 

صفحات  -

تاریخ انتشار 2017